2-Benzoylbenzoic acid
Synthesis- Product Name
- 2-Benzoylbenzoic acid
- CAS No.
- 85-52-9
- Chemical Name
- 2-Benzoylbenzoic acid
- Synonyms
- OBBA;skp10a;AKOS BBS-00000803;RARECHEM AL BO 1426;o-benzoyl-benzoicaci;2-benzoyl-benzoicaci;o-Carboxybenzophenone;2-BENZOYLBENZOIC ACID;2-CARBOXYBENZOPHENONE;OTAVA-BB BB7020401721
- CBNumber
- CB4741530
- Molecular Formula
- C14H10O3
- Formula Weight
- 226.23
- MOL File
- 85-52-9.mol
2-Benzoylbenzoic acid Property
- Melting point:
- 126-129 °C (lit.)
- Boiling point:
- 257-265 °C (lit.)
- Density
- 1.2022 (rough estimate)
- refractive index
- 1.5767 (estimate)
- Flash point:
- 257°C
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Crystalline Powder
- pka
- pK1: 3.54 (25°C)
- color
- Almost white to slightly beige
- Water Solubility
- 284mg/L at 20℃
- BRN
- 1107841
- InChIKey
- FGTYTUFKXYPTML-UHFFFAOYSA-N
- LogP
- 1.4 at 35℃
- CAS DataBase Reference
- 85-52-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzoic acid, 2-benzoyl-(85-52-9)
- EPA Substance Registry System
- Benzoic acid, 2-benzoyl- (85-52-9)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 2
- RTECS
- DG3600000
- TSCA
- Yes
- HS Code
- 29183000
- Hazardous Substances Data
- 85-52-9(Hazardous Substances Data)
- Toxicity
- LD50 orl-rat: 4600 mg/kg GTPZAB 15(11),52,71
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B12385
- Product name
- 2-Benzoylbenzoic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $24.36
- Updated
- 2024/03/01
- Product number
- B12385
- Product name
- 2-Benzoylbenzoic acid
- Purity
- 98%
- Packaging
- 500g
- Price
- $161
- Updated
- 2024/03/01
- Product number
- B0103
- Product name
- 2-Benzoylbenzoic Acid
- Purity
- >99.0%(T)
- Packaging
- 25g
- Price
- $21
- Updated
- 2024/03/01
- Product number
- A13281
- Product name
- 2-Benzoylbenzoic acid
- Purity
- 98+%
- Packaging
- 50g
- Price
- $33.65
- Updated
- 2024/03/01
- Product number
- A13281
- Product name
- 2-Benzoylbenzoic acid, 98+%
- Packaging
- 250g
- Price
- $91.65
- Updated
- 2024/03/01
2-Benzoylbenzoic acid Chemical Properties,Usage,Production
Synthesis
In the presence of aluminum trichloride, phthalic anhydride and benzene are condensed and obtained by hydrolysis. The hydrochloric acid gas by-product in the reaction should preferably be absorbed into dilute hydrochloric acid for subsequent use. The industrial benzoylbenzoic acid is white to beige powder, the purity is above 97%, and the initial melting point of the dry product is ≥126.0%.
Chemical Properties
ALMOST WHITE TO SLIGHTLY BEIGE CRYSTALLINE POWDER
Uses
2-Benzoylbenzoic Acid is a reagent that is used in the synthesis of BzATP Triethylammonium Salt, which is a selective P2X purinergic agonist. It is more potent than ATP at homodimeric P2X7 receptors.
Synthesis Reference(s)
Journal of the American Chemical Society, 70, p. 2758, 1948 DOI: 10.1021/ja01188a035
The Journal of Organic Chemistry, 39, p. 2051, 1974 DOI: 10.1021/jo00928a016
Flammability and Explosibility
Not classified
Safety Profile
Moderately toxic by ingestion.When heated to decomposition it emits acrid smoke andirritating vapors.
Purification Methods
Recrystallise the acid from *C6H6 or cyclohexane, but it is best recrystallised by dissolving in a small volume of hot toluene and then adding just enough pet ether to cause turbidity, and cool. Dry it in a low vacuum at 80o. It can be sublimed at 230-240o/0.3mm [Bray et al. J Chem Soc 265 1957]. The S-benzylisothiuronium salt has m 177-178o (from EtOH). [Lewenz & Serijan J Am Chem Soc 75 4087 1953, Beilstein 10 H 747, 10 IV 2977.]
2-Benzoylbenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Benzoylbenzoic acid Suppliers
View Lastest Price from 2-Benzoylbenzoic acid manufacturers
- Product
- 2-Benzoylbenzoic acid 85-52-9
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000
- Release date
- 2024-03-25
- Product
- 2-Benzoylbenzoic acid 85-52-9
- Price
- US $10.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-28
- Product
- 2-Benzoylbenzoic acid 85-52-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-11-30